Allergy skin test have represented the primary diagnostic tool in allergy. Their characteristics, simplicity, rapidity of performance, low cost and high sensitivity explain the key position that skin test occupies in allergy. However, one of the
main
limitations of the skin test is that the cutaneous reactivity is affected by multiple factors, such as areas of body, age, circadian rhythm, seasonal variation, drug and etc. The circadian rhythm and seasonal variation of skin test is well known
but
day-to-day variation of cutaneous reactivity is not elucidated.
The biorhythm theory suggests that there is an inherent rhythmicity to man's performance capacity, consisting of a 23-day physical cycle, a 28-day emotional cycle, a 33-day intellectual cycle. Theoretically, the cycle begin at birth and terminate
at
death.
We studed the correlation between day-today variation of sin test reactivity and biorhythm. But we cannot find a difference in skin test reactivity between critical day, positive state and negative state in biorhythm.
In conclusion, There is no relationships between day-to-day variation of skin test reactivity and biorhythm.
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